Proinflammatory Effects of Ubiquitin-Specific Protease 5 (USP5) in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Figure 3

USP5 aggravated proinflammatory cytokine production in IL-1β-treated RA-FLS. mRNA (a) or secreted protein (b) levels of TNF-α, IL-6, and MMP1 in USP5-overexpressed RA-FLS after IL-1β (10 ng/ml) treatment for 9 hours. mRNA (c) or secreted protein (d) levels of TNF-α, IL-6, and MMP1, in USP5-silenced RA-FLS after IL-1β (10 ng/ml) treatment for 9 hours. , .

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