Serum YKL-40 Levels Are Associated with the Atherogenic Index of Plasma in Children

Table 4

Multivariate linear regression analysis for lipid parameters with serum YKL-40.

	Concentration of serum YKL-40
Variables^‡	Unadjusted		Multivariable adjusted
	(95% CI)	value	aβ (95% CI)	value
Total cholesterol	0.015 (-0.451–0.482)	0.948	0.022 (-0.438–0.482)	0.925
LDL-C	0.057 (-0.236–0.351)	0.702	-0.004 (-0.298–0.288)	0.979
HDL-C	-0.420 (-0.759–-0.082)	0.015	-0.221 (-0.590–0.148)	0.240
Triglyceride	0.246 (0.095–0.398)	0.001	0.204 (0.048–0.360)	0.003
TG to HDL-C ratio	0.030 (0.011–0.049)	0.002	0.023 (0.004–0.043)	0.019
AIP (log TG to HDL-C ratio)	0.209 (0.088–0.329)	0.001	0.164 (0.036–0.292)	0.012

Abbreviation: AIP: atherogenic index of plasma; aOR: adjusted odds ratio; CI: confidence interval; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglyceride. Outcomes derived from generalized linear regression analysis with gamma function for the concentration of YKL-40 associated with individual lipid profile level as a continuous variable, adjusting with age, gender, and BMI -score. ^‡Log transformed for lipid profiles. Numbers in bold indicate a significant difference ().