High Mean Platelet Volume Associates with In-Hospital Mortality in Severe Pneumonia Patients
Table 1
Comparison of baseline characteristics.
Variables
Total ()
()
()
value
Demographic data
Age (years)
79 (63, 84)
79 (58, 83)
80 (67, 86)
0.273
Sex (male)
75, 65.2%
39, 70.9%
36, 60.0%
0.220
HAP
20, 17.4%
11, 20.0%
9, 15.0%
0.480
Underlying diseases
Hypertension
67, 58.3%
34, 61.8%
33, 55.0%
0.459
Diabetes mellitus
32, 27.8%
13, 23.6%
19, 31.7%
0.337
Coronary heart disease
16, 13.9%
4, 7.3%
12, 20.0%
0.049
Stroke
38, 33.0%
20, 36.4%
18, 30.0%
0.469
COPD
29, 25.2%
19, 34.5%
10, 16.7%
0.027
Chronic kidney disease
14, 12.2%
8, 14.5%
6, 10.0%
0.456
Chronic liver disease
7, 6.1%
3, 5.5%
4, 6.7%
1.000
Radiological findings
Bilateral pneumonia
87, 75.7%
42, 76.4%
45, 75.0%
0.865
>2-zone involvement
71, 61.7%
33, 60.0%
38, 63.3%
0.713
Pleural effusion
37, 32.2%
18, 32.7%
19, 31.7%
0.903
Clinical outcomes
Mechanical ventilation
78, 67.8%
32, 58.2%
46, 76.7%
0.034
Vasopressor use
45, 39.1%
18, 32.7%
27, 45.0%
0.178
CRRT
41, 35.7%
12, 21.8%
29, 48.3%
0.003
ICU LOS (days)
11 (7, 18)
13 (8, 18)
9 (5, 21)
0.317
Hospital LOS (days)
16 (9, 27)
18 (11, 28)
14 (8, 25)
0.083
In-hospital death
63, 54.8%
17, 30.9%
46, 76.7%
<0.001
Clinical data
MAP (mmHg)
83 (71, 97)
82 (71, 102)
83 (72, 95)
0.906
Heart rate (rate/min)
0.536
Respiratory rate (rate/min)
0.371
Body temperature (°C)
0.847
APACHE II score
20 (15, 24)
18 (15, 23)
23 (17, 27)
0.005
Laboratory results
Total bilirubin (umol/L)
13.0 (9.0, 21.8)
10.8 (7.4, 17.1)
14.0 (10.2, 25.4)
0.011
Albumin (g/L)
28.7 (26.8, 32.0)
29.9 (28.0, 32.1)
28.2 (25.4, 31.1)
0.064
Serum urea (mmol/L)
11.1 (8.1, 17.6)
10.0 (6.3, 15.1)
12.7 (9.2, 19.7)
0.007
Serum creatinine (μmol/L)
120.4 (83.3, 187.8)
96.9 (73.7, 136.3)
130.8 (92.0, 213.8)
0.005
RBC (1012/L)
0.960
HCT (%)
0.970
Hemoglobin (g/L)
0.260
WBC (109/L)
12.5 (8.3, 18.0)
14.1 (8.9, 18.9)
11.4 (8.1, 16.5)
0.064
Neutrophil count (109/L)
11.0 (7.1, 15.0)
11.6 (8.0, 16.6)
9.6 (7.0, 13.9)
0.104
Lymphocyte count (109/L)
0.7 (0.4, 1.0)
0.8 (0.4, 1.2)
0.7 (0.4, 0.8)
0.093
Platelet count (109/L)
222 (147, 288)
246 (203, 321)
168 (113, 245)
<0.001
PDW (fL)
12.8 (11.0, 14.5)
11.1 (9.7, 12.7)
13.6 (12.8, 15.5)
<0.001
Data are or medians (25th-75th percentile) or number and percentage. MPV: mean platelet volume; HAP: hospital-acquired pneumonia; COPD: chronic obstructive pulmonary disease; CRRT: continuous renal replacement therapy; MAP: mean arterial pressure; APACHE: acute physiology and chronic health evaluation; LOS: length of stay; RBC: red blood cell; HCT: hematocrit; WBC: white blood cell; PDW: platelet distribution width.
