High Mean Platelet Volume Associates with In-Hospital Mortality in Severe Pneumonia Patients

Table 2

Independent predictors of in-hospital mortality by univariate and multivariate Cox regression analysis.

Factors	HR (95% CI)
Univariate Cox analysis
APACHE II score	1.098 (1.064-1.133)	<0.001
Vasopressor use	2.778 (1.670-4.622)	<0.001
Mechanical ventilation	2.228 (1.205-4.119)	0.011
CRRT	2.446 (1.473-4.062)	0.001
Coronary heart disease	1.810 (0.934-3.508)	0.079
Age	1.018 (0.999-1.038)	0.059
Albumin	0.935 (0.884-0.989)	0.019
Serum urea	1.042 (1.018-1.067)	<0.001
Serum creatinine	1.001 (1-1.002)	0.060
Multivariate Cox analysis^a
COPD	1.937 (1.017-3.688)	0.044
Vasopressor use	1.842 (1.005-3.373)	0.048
CRRT	1.956 (1.004-3.809)	0.048
APACHE II	1.074 (1.025-1.126)	0.003

^aCovariates included in multivariate analysis: age, sex, coronary heart disease, COPD, APACHE II, mechanical ventilation, vasopressor use, CRRT, albumin, serum creatinine, and serum urea.
MPV: mean platelet volume; APACHE: acute physiology and chronic health evaluation; COPD: chronic obstructive pulmonary disease; CRRT: continuous renal replacement therapy; HR: hazard ratio; CI: confidence interval.