Combinational Pretreatment of Colony-Stimulating Factor 1 Receptor Inhibitor and Triptolide Upregulates BDNF-Akt and Autophagic Pathways to Improve Cerebral Ischemia

Figure 8

TP and Ki20227 regulate autophagy pathway. (a) Western blot images of Atg5, p62, LC3, Beclin1, and GADPH of experimental groups. Quantitative analyses of (b) p62 expression, (c) LC3II/I expression, (d) Beclin1 expression, and (e) Atg5 expression. Data were expressed as . One-way ANOVA with Tukey’s tests, . The WT vs. WT+stroke and WT+K vs. WT+stroke+K groups, , ; the WT+stroke+TP and WT+stroke+K groups vs. WT+stroke group, ^#, ^###; the WT+stroke+K+TP group vs. WT+stroke+TP and WT+stroke+K groups, ^{^^^}.

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