To study the effects of the probiotic administration on bacterial overgrowth, quality of life, gastrointestinal (GI) symptoms, and weight loss after surgery.
Prospective randomized controlled trial
35 RYGB patients. Control group () Probiotic group ()
Supplementation with 2.4 billion colonies of Lactobacillus daily postoperatively
6 months
(1) Statistically significant reduction in bacterial overgrowth. (2) Higher postoperative B12 levels (3) Greater percent excess weight loss
To investigate the effect of probiotic supplementation on inflammatory factors, anthropometric indices, and vitamin B12, folate, homocysteine, and 25-hydroxy vitamin D3 levels in One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) surgery patients.
Total 16 weeks (4 weeks before surgery to 12 weeks after surgery)
(1) Significant improvement in serum inflammatory markers including reduction in TNF-α in the probiotic group. (2) Percent weight loss and decreased BMI in the probiotic group. (3) No significant difference in serum levels of vitamin B12, folate, and homocysteine between the placebo and probiotic groups
100 morbidly obese subjects with nonalcoholic fatty liver disease who underwent LSG.
2 groups: probiotic (2 capsules per day of Bio-25 Supherb) group () and placebo group ()
6 months
Microbiota diversity increased in both the groups after 6 months of surgery and decreased at 12 months after surgery. No improvements were seen on hepatic, inflammatory, and clinical outcomes.