Gene Expression Profiling of Mediators Associated with the Inflammatory Pathways in the Intestinal Tissue from Patients with Ulcerative Colitis

Table 3

Gene expression associates with clinical outcomes.

Gene expression	value	Association with clinical outcome	Pathways involved with IBD
↑ IRGM		Medical treatment response to aminosalicylates (5-ASAs)	Autophagy
↑ FOXO4		Histological remission	Immune response
↑ CTLA4		Histological activity index score
↓ SLC26A3		Clinical course: the course of the same initial activity and prolonged remission	Solute transport
↑ SLC39A4		Evolution: tendency to years of evolution of between 10 and 15 years
↑ SOD2		Severe histological activity	Oxidative stress
↑ TDO2		Clinical course: characterized by the presence of initial activity and then prolonged remission more than 5 years
↑ ALDOB		Evolution: early age at diagnosis of less than 40 years	Carbohydrate metabolism
↑ ALDOB		Clinical course: prolonged benign clinical course characterized by the presence of higher initial activity and remission at 5 years