Association of Circulating Omentin-1 with Osteoporosis in a Chinese Type 2 Diabetic Population
Table 3
Binary logistic regression analyses of variables contributing to osteoporosis in patients with T2DM.
Variables
Univariate analysis
Multivariate analysis
OR (95% CI)
OR (95% CI)
Omentin-1
0.031
1.031 (1.005-1.058)
0.020
0.034
1.035 (1.001-1.070)
0.046
Sex
2.365
10.649 (4.322-26.242)
0.0001
1.976
7.214 (2.387-21.804)
0.0001
Age
0.085
1.089 (1.038-1.142)
0.0001
0.077
1.080 (1.018-1.146)
0.010
Diabetic duration
0.009
1.009 (0.951-1.070)
0.766
BMI
-0.107
0. 898 (0.803-1.005)
0.061
TC
0.130
1.139 (0.848-1.529)
0.387
TG
0.224
1.251 (0.955-1.640)
0.104
HDL-C
-0.826
0.438 (0.142-1.355)
0.152
LDL-C
0.156
1.169 (0.799-1.710)
0.421
apoA
0.291
1.337 (0.316-5.650)
0.693
apoB
0.401
1.494 (0.387-5.766)
0.561
FBG
-0.075
0.928 (0.837-1.030)
0.159
HbA1c
-0.056
0.946 (0.806-1.110)
0.493
WBC
-0.019
0.981 (0.787-1.224)
0.866
Neutrophil count
0.056
1.058 (0.834-1.342)
0.641
Lymphocyte count
-0.332
0.717 (0.369-1.395)
0.327
NLR
0.041
1.042 (0.895-1.214)
0.595
Hb
-0.060
0.942 (0.914-0.971)
0.0001
-0.044
0.957 (0.922-0.993)
0.020
TBIL
-0.106
0.900 (0.821-0.985)
0.023
GGT
-0.027
0.973 (0.950-0.997)
0.030
Serum albumin
-0.100
0.905 (0.820-0.999)
0.047
UA
-0.002
0.998 (0.994-1.002)
0.304
Ca
0.029
1.030 (0.499-2.125)
0.937
P
0.177
1.194 (0.232-6.147)
0.832
ALP
0.015
1.015 (1.000-1.030)
0. 052
PTH
0.004
1.004 (0.993-1.016)
0.477
25(OH)D
-0.015
0.986 (0.948-1.024)
0.456
TRACP-5b
0.095
1.100 (0.839-1.442)
0.489
Hypertension
0.403
1.497 (0.659-3.400)
0.335
CHD
1.139
3.125 (0.601-16.249)
0.176
Stroke
0.570
1.768 (0.716-4.366)
0.216
PAD
1.312
3.712 (0.960-14.361)
0.057
DN
1.000
2.719 (1.238-5.972)
0.013
DR
0.714
2.042 (0.483-8.634)
0.332
DPN
-0.239
0.788 (0.338-1.837)
0.580
Beta is the standardized coefficient and measures the influence of each variable on osteoporosis; OR is the odds ratio and refers to the risk of osteoporosis.