Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma

Figure 2

DE circRNAs in tumor tissues and adjacent normal tissues from GC patients, screening DE miRNAs and DE mRNAs, and visualization of the circRNA-miRNA-mRNA regulatory network. (a) The box plot shows variations in circRNA expression. (b) The heat map shows DE circRNAs in 6 tumors (T) and 6 normal (N) tissues. Gene expression profiles are shown in rows. “Red” suggests a high relative expression, and “green” indicates low relative expression. (c) Based on DE miRNAs and circRNA-related miRNAs, Venn diagrams were used to select the overlapping 10 miRNAs; based on DE mRNAs and miRNA-related mRNAs, Venn diagrams were used to select the overlapping 33 mRNAs.

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