Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma

Figure 7

Display of neighboring genes connected to THBS1, FN1, CALM1, COL4A1, CTGF, and IGFBP5 in GC. THBS1, FN1, CALM1, COL4A1, CTGF, and IGFBP5 were used as seed genes (indicated with thick black borders) to automatically harvest all other genes identified as altered in GC. Multidimensional genomic details are shown for COL4A1, FN1, CTGF, and CALM1 seed genes. Dark red indicates an increased frequency of alterations (defined by mutation, copy number amplification, or homozygous deletion) in GC. Shown in the figure are the full and pruned networks containing all or part neighbors of all query genes generated; the neighboring genes connected to COL4A1, FN1, CTGF, and CALM1 are filtered by alteration (%).