ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis

<div>Ad-O/E-ADAR1 ameliorates sepsis in a mouse model. (a, b) The small intestine, spleen, and lymph nodes were dissected to observe morphologic changes in the gross specimens. (c, d) Intestinal leakage assayed by FITC-dextran gavage (100x) and measurements of FITC-dextran concentrations in the blood. (e, f) Representative images of villar injury in the small intestine and scored by HE staining (100x). 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Mediators of Inflammation

fig1

Figure 1

Figure 1: ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis 