lncRNA IGHCγ1 Acts as a ceRNA to Regulate Macrophage Inflammation via the miR-6891-3p/TLR4 Axis in Osteoarthritis

Figure 2

lncRNA IGHCγ1 promoted macrophage proliferation and migration. (a) Real-time PCR showed lncRNA IGHCγ1 expression after overexpression in macrophages (; ). (b) Real-time PCR presented IGHCγ1 expression after knockdown in macrophages (; ). (c) CCK-8 revealed that lncRNA IGHCγ1 enhanced the proliferation of macrophages (; ; ). (d) siRNA of IGHCγ1 inhibited macrophage proliferation assayed by CCK-8 (; compared with the control group, ; ). (e) IGHCγ1 promoted macrophage proliferation when it was upregulated in cells assayed by EdU (representative pictures of EdU assays). (f) lncRNA IGHCγ1 promoted macrophage proliferation (data of three repeated EdU experiments; compared with controls, ).

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