Mediators of Inflammation / 2020 / Article / Fig 4

Research Article

lncRNA IGHCγ1 Acts as a ceRNA to Regulate Macrophage Inflammation via the miR-6891-3p/TLR4 Axis in Osteoarthritis

Figure 4

miR-6891-3p promoted macrophage proliferation. (a) miR-6891-3p was decreased in PBMCs of OA patients (cases/controls: 36/30; ). (b) Reduced miR-6891-3p in macrophages activated by LPS (1 μg/ml) (; ). (c) As demonstrated by real-time PCR, miR-6891-3p inhibitors efficiently inhibited its expression in macrophages (; ). (d) CCK-8 showed elevated proliferation of pTHP-1 cells administrated with miR-6891-3p inhibitors (; ; ).

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