Research Article

Monocyte/Lymphocyte Ratio and Cardiovascular Disease Mortality in Peritoneal Dialysis Patients

Table 1

Baseline characteristics of the study population.

VariablesLowest MLR tertileMiddle MLR tertileHighest MLR tertile value
()MLR 0.29-0.45 () ()

Age (years)<0.001
Male sex (%)272 (46.7)346 (59.1)379 (64.8)<0.001
Hypertension (%)408 (0.70)404 (69.1)432 (73.8)0.160
A history of CVD (%)108 (18.5)89 (15.2)104 (17.8)0.290
Diabetes (%)129 (22.1)129 (22.1)160 (27.4)0.051
CCI<0.001
Current smoking (%)26 (4.5)32 (5.5)29 (5.0)0.729
Current drinking (%)5 (0.9)12 (2.1)8 (1.4)0.225
ACEI/ARB use (%)195 (33.0)195 (33.0)213 (36.4)0.455
β-Blocker use (%)134 (23.0)112 (19.1)140 (23.9)0.112
Statin use (%)69 (11.8)72 (12.3)94 (16.1)0.067
BMI (kg/m2)0.906
Systolic BP (mmHg)0.477
Diastolic BP (mmHg)0.778
24 h urine output (ml)600 (200-1050)700 (300-1100)650 (200-1000)0.062
Monocytes (109/l)0.003
Lymphocytes (109/l)0.005
Albumin (g/dl)0.107
Cholesterol (mg/dl)0.421
Triglycerides (mg/dl)0.686
LDL (mg/dl)0.506
HDL (mg/dl)0.411
Serum uric acid (mg/dl)0.118
hs-CRP (mg/l)21.8 (5.40-82.7)9.9 (2.4-37.2)6.6 (2.3-22.6)0.746
NT-pro-BNP (pg/ml)3207 (1141-8789)2810 (504-14675)2135 (1034-5757)0.464
eGFR (ml/min/1.73 m2)5.71 (4.31–8.40)5.69 (4.29–8.64)5.68 (4.23–7.44)0.367

MLR: monocyte-to-lymphocyte ratio; CVD: cardiovascular disease; CCI: Charlson comorbidity index; ACEI/ARB: angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; BP: blood pressure; LDL: low-density lipoprotein; HDL: high-density lipoprotein; hs-CRP: high-sensitivity C-reactive protein; NT-pro-BNP: N-terminal probrain natriuretic peptide; eGFR: estimated glomerular filtration rate.