High-Intensity Interval Training Improves Physical Function, Prevents Muscle Loss, and Modulates Macrophage-Mediated Inflammation in Skeletal Muscle of Cerebral Ischemic Mice

Figure 4

High-intensity interval training improved gait and pulmonary functional parameters. (a) Schematic diagram of labeled footprint and 3D footprint intensity charts. Graph demonstrates statistical differences in the average run characterization parameter in each group, including stand (s) (b), swing (s) (c), duty cycle (%) (d), mean intensity (e), duration (s) (f), average speed (cm/s) (g), and cadence (step/s) (h). (i) The respiration curve illustrates the changes of volume of the plethysmograph induced by the volatility of the mouse’s thorax in each group. The graph demonstrates statistical differences in the average pulmonary functional parameter in each group, including respiratory frequency (j), tidal volume (k), minute ventilation (mL) (l), peak inspiratory flow (mL/s) (m), peak expiratory flow (mL/s) (n), and enhanced pause (o). Values are expressed as the of the mean. and compared with the sham group; ^# and ^## compared with the MCAO group as determined by one-way ANOVA (Tukey’s multiple comparison test) for the data with normal distribution. The letters for no significance were not shown. Abbreviation: RF: right forelimb; RH: right hindlimb; LF: left forelimb; LH: left hindlimb.

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