Diannexin Can Ameliorate Acute Respiratory Distress Syndrome in Rats by Promoting Heme Oxygenase-1 Expression

Figure 2

Diannexin reduces pathological lung injury in ARDS rats. (a) We observed typical pathological lung injury in ARDS rats. There was significant infiltration of inflammatory cells into the lung tissue. Significantly thickened and broken alveolar walls and severe edema were noted in the alveolar capillaries. Compared with the ARDS group, the D group showed improved alveolar morphology, but this improvement was partially blocked by the HO-1 inhibitor in the DH group. (b) Histogram showing the scores of the four study groups that reflect the extent of pathological lung damage as assessed by an independent pathologist. Data are presented as the . Statistical analysis was performed using the ANOVA test.

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