Diannexin Can Ameliorate Acute Respiratory Distress Syndrome in Rats by Promoting Heme Oxygenase-1 Expression

Figure 4

Diannexin regulates the level of proapoptotic and antiapoptotic proteins in the lung tissue. (a) Western blot showing the protein levels of HO-1, NF-κB, Bax, and Bcl-xL. Administration of diannexin in the D group significantly reduced the level of proapoptotic protein Bax but increased the level of antiapoptotic protein Bcl-xL. The diannexin-induced effects were reversed by the HO-1 inhibitor in the DH group. (b) Histograms showing the relative levels of HO-1, NF-κB, Bax, and Bcl-xL using β-actin as the internal reference. Data are presented as the . Statistical analysis was performed using the ANOVA test.

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