LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure

Figure 1

Injection of LR12 reduced the liver inflammation and stimulated liver regeneration following TAA-induced ALF in mice. (a) H&E staining (magnification, 200x and 400x) showing inflammatory cell infiltration and necrotic area (%) in the liver. (b) Serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). (c) Survival curve from mice with TAA-induced ALF (/group). (d) CLSM showing CK18 and PCNA staining in the liver. (e) Western blotting detected PCNA expression in the liver tissue. Data were presented as the (SD) (). , , and versus control group.

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