Research Article

LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure

Figure 3

LR12 promoted hepatocyte proliferation via macrophages in LO2 cells. (a) THP-1 cells were successfully differentiated into macrophages by PMA (100 ng/mL). (b) Immunofluorescence images of F4/80 staining and DAPI in macrophages. (c) CLSM showing CK18 and PCNA staining in LO2 cells stimulated with the macrophage supernatant. (d) Western blot analysis of PCNA in LO2 cells stimulated with the macrophage supernatant. (e) The LO2 cell cycle detected by flow cytometric analysis. (f) CCK-8 assay analysis of LO2 cell viability. Data were presented as the (SD). , , and versus control group.
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