LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure

<div>CCL20 neutralization aggravated the severity of TAA-induced ALF and inhibited liver regeneration. (a) Western blot analysis of PCNA in LO2 cells stimulated with TAA+LR12 or/and anti-CCL20 hAbs. (b) H&amp;E staining (magnification, 400x) of the liver tissues in mice treated with TAA+LR12 and normal rat IgG or anti-CCL20 mAbs. (c) The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum. (d) CLSM showing CK18 and PCNA staining in the liver tissues in mice treated with TAA+LR12 and normal rat IgG or anti-CCL20 mAbs. (e) Western blot analysis of PCNA in the liver tissues. 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Mediators of Inflammation

fig6

Figure 6

Figure 6: LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure 

Figure 6 | LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure 