Interleukin-1 Links Autoimmune and Autoinflammatory Pathophysiology in Mixed-Pattern Psoriasis

<div>IL-1 and IL23 induce CD4 CD161 precursors’ differentiation to classical Th-17 and Th-1 cells in the presence of IL-12. IL-1: interleukin-1; IL-23: interleukin-23; IL-12: interleukin-12; Th: T-helper cells.</div>

Mediators of Inflammation

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Figure 4

Figure 4: Interleukin-1 Links Autoimmune and Autoinflammatory Pathophysiology in Mixed-Pattern Psoriasis 