Investigation of Newly Diagnosed Drug-Naive Patients with Systemic Autoimmune Diseases Revealed the Cleaved Peptide Tyrosine Tyrosine (PYY 3-36) as a Specific Plasma Biomarker of Rheumatoid Arthritis

Figure 1

The scatter plots of the protein concentrations of plasma proteins (pg/ml) in drug-naive RA () patients versus age- and gender-matched healthy controls () with significant differences (one-way ANOVA, ; , ) measured by the Luminex MAGPIX technology. The cleaved peptide tyrosine tyrosine PYY (3-36) was detected as being a novel marker of early-onset therapy-naive rheumatoid arthritis (RA) (). The arithmetic are demonstrated for each cytokine (pg/ml) of RA () patients versus age- and gender-matched healthy controls (). One dot is the average of two technical replicates.