Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer’s Disease Patients

Table 4

Analysis of association between MMP2 rs243865 (-1306 C/T) genotypes and clinical findings.

Parameter	CC ()	CT ()	TT ()	CM	DM	RM	OM
Age at onset, (y)				0.11/0.07	0.036/0.024	0.62/0.68	0.058/0.034
MoCA score,				0.32/0.29	0.16/0.13	1.00/0.92	0.14/0.13

Abbreviations: CM: codominant model; DM: dominant model; RM: recessive model; OM: overdominant; SD: standard deviation; MoCA: Montreal Cognitive Assessment; : number; y: years. values were calculated using Welch’s corrected -test. values adjusted for sex and APOEε4 positivity. is considered statistically significant.