Zataria multiflora and Pioglitazone Affect Systemic Inflammation and Oxidative Stress Induced by Inhaled Paraquat in Rats

Figure 5

Values of interferon gama (INF-γ) (a) and interleukin-10 (IL-10) (b) in the serum of control group (Ctrl), group exposed to paraquat aerosol at doses of 54 mg/m³ (PQ-54), and groups exposed to PQ-54 mg/m³ and treated with 5 and 10 mg/kg/day pioglitazone, 200 and 800 mg/kg/day Zataria multiflora, 0.03 mg/kg/day dexamethasone, and (Pio-5, Pio-10, Z-200, Z-800, Dexa 0.03, and Pio--200, respectively). The results are expressed as the ( in each group). compared to the control group. ⁺, ⁺⁺, and ⁺⁺⁺ compared to the PQ group. ^## and ^### compared dexamethasone treatment with other treated groups. ^$ and ^$$ compared to low dose of Zataria multiflora and pioglitazone groups. ^¥¥¥ comparison between with low dose of Zataria multiflora and pioglitazone groups. ^¥ and ^¥¥¥ compared to group. Comparisons between different groups were made using one-way ANOVA followed by Tukey’s multiple comparison test.

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