Zataria multiflora and Pioglitazone Affect Systemic Inflammation and Oxidative Stress Induced by Inhaled Paraquat in Rats

Table 1

Total and differential WBC counts in the blood of control group (Ctrl), group exposed to paraquat aerosol at doses of 54 mg/m³ (PQ-54), groups exposed to PQ-54 mg/m³ and treated with 5 and 10 mg/kg/day pioglitazone, 200 and 800 mg/kg/day Zataria multiflora, 0.03 mg/kg/day dexamethasone, and (Pio-5, Pio-1, Z-200, Z-800, Dexa 0.03, and , respectively).

White blood cells (WBC)	Total WBC	Neutrophil	Lymphocyte	Monocyte	Eosinophil
Ctrl
PQ-54
Z-200	^¥	^###	^¥¥¥	^##,¥	^###,¥¥¥
Z-800	^++,$	^++,###		^++,#	^++,$,###,¥¥
Pio-5	^++	^++,###		^##,¥	^++,##,¥¥
Pio-10	^+++,$	^+++,$$$	^+,$	^+,##	^+++,$$$
Pio--200	^+	^++,#	^++	^++,#	^+++
Dexa 0.03	^+	^+++		^+++	^+++

The results are expressed as the ( in each group). compared to the control group. ⁺, ⁺⁺, and ⁺⁺⁺ compared to the PQ group; ^# and ^### compared to dexamethasone. ^$ and ^$$$ compared to low dose of Zataria multiflora and pioglitazone groups. ^¥ compared to group. Comparisons between different groups were made using one-way ANOVA followed by Tukey’s multiple comparison test.