Research Article
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury
Figure 3
EZH2 regulated inflammation and glycolysis through HIF-1α. (a, b) qRT-PCR and Western blot were performed to detect the overexpression of HIF-1α in microglia, respectively. vs oe-NC group. (c) qRT-PCR were used to detect inflammatory factors IL-6, TNF-α, and IL-17 and glycolysis-related gene PKM2, GLUT1, and HK2 expressions. vs Control group; # vs oe-HIF-1α group. (d) Western blot detected inflammatory factors IL-6, TNF-α, and IL-17 and glycolysis-related gene PKM2, GLUT1, and HK2 expressions. vs. Control group; # vs. oe-HIF-1α group.
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