Research Article
IL-38 Alleviates Inflammation in Sepsis in Mice by Inhibiting Macrophage Apoptosis and Activation of the NLRP3 Inflammasome
Figure 7
Effects of IL-38 on CLP-induced inflammation and markers of vital organ injury in septic mice. (a–g) Serum levels of indicated inflammatory biomarkers in CLP mice treated with IL-38 or anti-IL-38 antibody. vs. the sham group; ## vs. CLP control. (h) Mice that underwent CLP were treated with IL-38 or PBS. Mice were sacrificed 24 h after CLP. H&E staining and histological scores of the lungs, kidneys, and liver. ## vs. the PBS group. Results are shown for six mice per group. # and ## vs. PBS control.
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