Particulate Matter-Induced Acute Coronary Syndrome: MicroRNAs as Microregulators for Inflammatory Factors

Table 4

Target inflammatory genes and miRNAs.

Target inflammatory genes	miRNAs	Related cell/organ/disease	Author
CD14	miR-199a-3p, miR-199a-5p, and miR-21-5p	RAW264.7 macrophage cell line, lipopolysaccharide- (LPS-) induced proinflammatory cytokine release, and LPS-induced septic shock	[91]
EDN1 (putative target of miRNA	miR-199	Liver sinusoidal endothelial cells (rLSEC) derived from ethanol-fed rats	[94]
IL-1β	miR-448	Autoimmune diseases	[95]
IL-6	miR-181c	INS-1 cells	[96]
IL-6	miR-410	Lupus nephritis, systemic lupus erythematosus (SLE) in kidney tissue of MRL/lpr mice	[97]
MCP-1	miR-124a	Synoviocytes from rheumatoid arthritis	[98]
TLR2	miR-146a	BLP-stimulated human THP-1 promonocytic cells, innate immune response to infection	[99]
TLR2	miR-105	Primary human keratinocytes, challenge with Porphyromonas gingivalis (a Gram-negative bacterium that triggers TLR-2 and TLR-4)	[100]
TLR2	miR19a/b	Rheumatoid fibroblast-like synoviocytes, rheumatoid arthritis (RA)	[101]
TNF-α	miR-181a-5p	Dendritic cells	[102]