IL-9 and IL-10 Single-Nucleotide Variants and Serum Levels in Age-Related Macular Degeneration in the Caucasian Population
Table 5
The impact of IL-9 rs1859430 and rs11741137 on early AMD in males.
Model
Genotype/allele
OR (95% CI)
value
AIC
IL-9 rs1859430
Codominant
GA vs. GG
0.547 (0.302-0.991)
0.047
342.864
AA vs. GG
1.667 (0.54-5.010)
0.363
Dominant
GA+AA vs. GG
0.671 (0.390-1.155)
0.150
344.355
Recessive
AA vs. GA+GG
1.966 (0.661-5.843)
0.224
342.961
Overdominant
GA vs. GG+AA
0.526 (0.292-0.948)
0.033
341.702
Additive
A
0.863 (0.562-1.327)
1.327
346.005
IL-9 rs11741137
Codominant
CT vs. CC
0.574 (0.317-1.041)
0.068
341.517
TT vs. CC
3.000 (0.751-11.983)
0.120
Dominant
CT+TT vs. CC
0.720 (0.415-1.248)
0.242
345.071
Recessive
TT vs. CT+CC
3.476 (0.878-13.769)
0.076
342.969
Overdominant
CT vs. CC+TT
0.543 (0.301-0.979)
0.042
342.175
Additive
T
0.929 (0.590-1.464)
0.751
346.357
Only two genotypes were determined. OR: odds ratio; CI: confidence interval; p: significance level and Bonferroni corrected significance level when ; AIC: Akaike information criterion.
