Association between Monocyte to High-Density Lipoprotein Cholesterol Ratio and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study
Table 1
Comparison of clinical characteristics between the subjects with and without NAFLD.
Variables
With NAFLD ()
Without NAFLD ()
value
value
Age (year)
52 (45–59)
47 (40–55)
-19.838
<0.001
Gender (male/female, )
3683/1282
4565/4659
808.317†
<0.001
BMI (kg/m2)
25.96 (24.34–27.77)
22.39 (20.65–24.26)
-65.179
<0.001
Waist circumference (cm)
91 (86–96)
80 (74–86)
-61.779
<0.001
Systolic blood pressure (mmHg)
133 (122–144)
121 (111–133)
-36.960
<0.001
Diastolic blood pressure (mmHg)
82 (75–89)
74 (67–82)
-38.525
<0.001
Alanine aminotransferase (U/L)
26 (18–37)
16 (12–22)
-48.523
<0.001
Aspartate aminotransferase (U/L)
22 (18–27)
19 (16–23)
-29.232
<0.001
γ-Glutamyl transferase (U/L)
34 (22–55)
17 (12–27)
-50.255
<0.001
Triglyceride (mmol/L)
1.72 (1.24–2.46)
1.00 (0.73–1.41)
-54.937
<0.001
Total cholesterol (mmol/L)
4.94 (4.36–5.58)
4.59 (4.07–5.17)
-21.749
<0.001
HDL-C (mmol/L)
1.10 (0.95–1.30)
1.32 (1.12–1.55)
-38.557
<0.001
LDL-C (mmol/L)
2.70 (2.28–3.16)
2.51 (2.12–2.95)
-15.274
<0.001
Fasting plasma glucose (mmol/L)
5.03 (4.70–5.55)
4.75 (4.49–5.05)
-32.586
<0.001
HbA1c (%)
7.00 (6.70–7.50)
6.70 (6.50–7.00)
-28.698
<0.001
Serum uric acid (μmol/L)
369 (313–430)
298 (246–358)
-42.845
<0.001
MHR
5.35 (4.18–6.84)
4.53 (3.48–5.93)
-23.423
<0.001
Data are presented as median (IQR) due to skewed distribution. †χ2 value; BMI: body mass index; HbA1c: glycated hemoglobin A1c; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; MHR: monocyte to HDL-C ratio; NAFLD: nonalcoholic fatty liver disease.
