Research Article

Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury

Figure 3

Heat map demonstrating the gene expression in the three experimental groups PT + HS, PT, and Ctrl; each column represents one animal. The high expression value of genes is shown in red and the low expression in green. Significantly upregulated genes of the pathways positive regulation of IL-6 production (a), neutrophil chemotaxis (b), positive regulation of cell adhesion (c), and toll-like receptor signaling pathway (d), as well as significantly downregulated genes of the pathways B-cell activation (e) and T-cell activation (f) are shown.