The Role of CD40 in Allergic Rhinitis and Airway Remodelling

Figure 5

(a) Goblet cell numbers of control, AR, intravenous CD40 siRNA, and nasal CD40 siRNA groups were detected by PAS staining. There was no significant difference in goblet cell numbers between AR, CD40 siRNA treatment, and control groups. All values >0.05. (b) Collagen deposition of control, AR, intravenous CD40 siRNA, and nasal CD40 siRNA groups was detected by MT staining. In this study, AR mice expressed significantly more collagen deposition, compared to control group. Mice treated nasally or intravenously with CD40 siRNA expressed significantly less collagen deposition, compared with AR mice. values <0.05 were considered as significance. (c) Goblet cell numbers of control, AR, intravenous CD40 siRNA, and nasal CD40 siRNA groups were detected by PAS staining. (d) Collagen deposition of control, AR, intravenous CD40 siRNA, and nasal CD40 siRNA groups was detected by MT staining.

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