The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors

Figure 1

Schematic presentation of the experimental protocol. The cells in blank group were treated only with ATP (5 mM, 30 min). The cells in LPS control group were treated with LPS (10 μg/ml, 6 h) and ATP (5 mM, 30 min). In RT group, the cells that had been treated with 10 μM AEA for 24 h induced with LPS (10 μg/ml, 6 h), and in OT group, the cells were treated with AEA (10 μM, 24 h) after treatment with LPS (10 μg/ml, 6 h), and the last two groups were treated with ATP (5 mM, 30 min) after LPS induction.