Mediators of Inflammation / 2021 / Article / Fig 5

Research Article

The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors

Figure 5

AM-251 and AMG-9810 pretreatment reversed the inhibitory effects of AEA on inflammasome components. Effect of various concentrations of AM-251 and AMG-9810 on IL-1β secretion in (b) AEA-treated AGS cells. (b) qRT-PCR and (c) Western blot of inflammasome-related genes in LPS-stimulated AGS cells in the presence or absence of AM-251 and AMG-9810. All experiments were performed in triplicate, and the results were obtained from at least two independent experiments. Data are expressed as . Indicates significantly changes compared to control group, , and ; #compared to LPS group, #, ##; $compared to RT group and $.
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