Activation of Opioid Receptors Attenuates Ischemia/Reperfusion Injury in Skeletal Muscle Induced by Tourniquet Placement

<div>Oxy treatment increased blood flow after tourniquet placement on the hind limb. (a) Representative images of blood perfusion in the mouse hind limb obtained using laser speckle contrast imaging. The red color on the image represents high blood flow to the limb while the blue color represents low blood flow. Quantification of perfusion in the ischemic hind limb before ischemia (b), during ischemia (c), and during reperfusion for 24 h (d). I/R: ischemia-reperfusion; Oxy: oxycodone. 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Mediators of Inflammation

fig1

Figure 1

Figure 1: Activation of Opioid Receptors Attenuates Ischemia/Reperfusion Injury in Skeletal Muscle Induced by Tourniquet Placement 