Identification of the Molecular Basis of Nanocurcumin-Induced Telocyte Preservation within the Colon of Ulcerative Colitis Rat Model

Figure 6

Photomicrographs of CD34 immunohistochemical stained sections in the colon. (a–c) The control group and (d-f) NC group both show numerous CD34 positive TCs (arrow) with long Tps (arrowhead) in the lamina propria close to the crypt epithelium, in between smooth muscle of muscularis mucosa, submucosa, between SMF of musculosa, in the myenteric plexus (star) and around blood vessels (BV). (g–i) The UC group reveals undetected TCs in the mucosa and submucosa. Few numbers of TCs are present in the musculosa and myenteric plexus (star). (j–l) The UC+NC group shows numerous TCs in all layers of the colon. Note: the endothelium of blood vessels (BV) reveals CD34 positive immune stain (CD34 immunostaining X400 insert in a and j X1000).