Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes

<div>INH and RIF markedly regulated the OS-antioxidant defense system and drug-metabolizing enzymes in rats. (a–e) The OS indices (LPOs) and levels of antioxidant enzymes (SOD, CAT, GSH, and GPx) in rats treated with INH and RIF were determined using specific commercial kits. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes 