Research Article

Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors

Table 1

Clinical characteristics of study patients at baseline.

CharacteristicsAll patients ()

Age (years) (26-89)
Gender, male19 (63%)
SAPS III (45-107)
TISS (26-57)
Leukocyte count (×103/μl) (2-35)
Comorbidities, number (% of total)
 Cardiovascular18 (60%)
 Pulmonary7 (23%)
 Hepatitis/pancreatitis1 (3%)
 Neurological9 (30%)
 Renal5 (17%)
 Diabetes9 (30%)
Primary site of infection, number (% of total)
 Lung1 (3%)
 Abdomen10 (33%)
 Blood7 (23%)
 Urinary tract3 (10%)
 Other7 (23%)
 Unknown2 (7%)

Data are represented as (range) or (%). SAPS III: Simplified Acute Physiology Score III; TISS: Therapeutic Intervention Scoring System.