Research Article
Sodium Houttuyfonate Ameliorates β-amyloid1-42-Induced Memory Impairment and Neuroinflammation through Inhibiting the NLRP3/GSDMD Pathway in Alzheimer’s Disease
Figure 5
SH inhibited the NLRP3/GSDMD pathway in PC12 cells. (a) The protein expressions of NLRP3, ASC, caspase-1, and GSDMD-N were measured by western blot. (b) The mRNA expressions of NLRP3, ASC, caspase-1, and GSDMD-N were measured by qRT-PCR. (c) The expression of NLRP3 was determined by immunofluorescence staining. (d) The expression of GSDMD-N was determined by immunofluorescence staining. , vs. the Control group; ##, vs. the Aβ1-42 group.
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