Research Article
Sodium Houttuyfonate Ameliorates β-amyloid1-42-Induced Memory Impairment and Neuroinflammation through Inhibiting the NLRP3/GSDMD Pathway in Alzheimer’s Disease
Figure 6
CY-09 enhanced the inhibitory effects of SH on proinflammatory cytokines and cell apoptosis in PC12 cells. (a) The protein expressions of NLRP3, ASC, caspase-1, and GSDMD-N were measured by western blot. (b) The levels of IL-6, IL-1β, IL-18, and TNF-α were detected by ELISA. (c) PC12 cell apoptosis was detected by flow cytometry. , vs. the Aβ1-42 group; ##, vs. the Aβ1-42+SH group.
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