The Signaling Pathway of PGE2 and Its Regulatory Role in T Cell Differentiation

<div>The process of PGE2 synthesis. Arachidonic acid is released from the membrane by phospholipase A2. Cyclooxygenases (COX-1 and COX-2) produce prostaglandin H2 (PGH2) from arachidonic acid. PGH2 is produced by prostaglandin synthase to produce PGI2, PGD2, PGE2, and PGF2α.</div>

Mediators of Inflammation

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Figure 1

Figure 1: The Signaling Pathway of PGE2 and Its Regulatory Role in T Cell Differentiation