Catheter-Based Radiofrequency Renal Sympathetic Denervation Decreases Left Ventricular Hypertrophy in Hypertensive Dogs

Table 3

Echocardiographic evaluation of structural cardiac changes in experimental dogs (control group (), sham-operated group (), and RDN group ()).

Group	LVEDD (mm)	IVST (mm)	LVPW (mm)	LVM (g)	LVMI (g/kg)	LVEF (%) (cm/s)	Peak E (cm/s)	Peak A (cm/s)	Peak E/A	LAD (mm)
Control group
Baseline			6.0 (5.0-7.0)
Preprocedure			6.0 (6.0-7.0)
6 months			6.0 (6.0-7.0)
Sham-operated group
Baseline			6.0 (6.0-7.0)
Preprocedure	^ad	^ad	8.0 (7.0-8.0)^ad	^ad	^ad		^ad		^ad
6 months	^ad	^ad	8.0 (7.0-9.0)^ad	^ad	^ad		^ad	^ad	^ad	^ad
RDN group
Baseline			6.0 (5.0-7.0)
Preprocedure	^ad	^ad	7.0 (7.0-8.0)^ad	^ad	^ad		^ad		^ad
6 months	^ad	^bc	6.1 (6.0-7.0)^bc	^bc	^bc		^bc		^bc

^aCompared with baseline, . ^bCompared with preprocedure, . ^cCompared with the sham-operated group, . ^dCompared with the control group, . LVEDD: left ventricular end-diastolic diameter; IVST: interventricular septal thickness; LVPW: left ventricular posterior wall; LVM: left ventricular mass; LVMI: left ventricular mass index; LVEF: left ventricular ejection fraction; peak E: early peak diastolic velocity; peak A: peak atrial velocity; peak E/A: the ratio of peak E to peak A; LAD: left atrial diameter.