Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes

Figure 1

Long-term diabetogenic effects of ALX and STZ on mice. T1D was induced as described in Methods, and parameters were evaluated at different time points. (a) Blood glucose levels and (b) body weight were evaluated on the 15^th, 30^th, 60^th, 90^th, and 180^th days following administration of the drugs. (c) Survival rate was monitored for 180 days (CT and STZ groups represented as overlapping lines). (d, e) Insulin tolerance test and (f, g) glucose tolerance test were evaluated on the 90^th and 180^th days. (h) Food and (i) water intake was evaluated for five days. Data are presented as , (5-6 animals per group).

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