Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation

<div>LncRNAs and their potential target genes in AF and SR patients. (a) Volcano plot of differentially expressed lncRNAs. Red and blue dots represent the high and low differential expression of lncRNAs, respectively. (b) Box plot of the LINC00636 expression in the two groups. (c) Map of binding sites between LINC00636 and miR-450a-2-3p. (d) Network map for LINC00636-related genes and miR-450a-2-3p. (e) GO and KEGG pathway enrichment analyses.</div>

Mediators of Inflammation

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Figure 1

Figure 1: Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation 

Figure 1 | Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation 