Monitoring Salivary Levels of Interleukin 1 Beta (IL-1β) and Vascular Endothelial Growth Factor (VEGF) for Two Years of Orthodontic Treatment: A Prospective Pilot Study

Table 2

Mean salivary output (pg/min) of patients (), 95% confidence interval, and significant values for IL-1β and VEGF during the treatment stages: baseline, alignment, space closure, and finishing. Comparisons by multivariate analysis of ANOVA: , .

	IL-1β				VEGF
		95% confidence interval for mean		Analysis of variance		95% confidence interval for mean		Analysis of variance
		Lower bound	Upper bound			Lower bound	Upper bound
Baseline (B)		22.4	96.6	0.002 B/SC		92.4	294.3	0.025 B/SC
Alignment (A)		76.7	185.8	NS		188.6	811.8	NS
Space closure (SC)		141.9	315.0	0.002 SC/B		336.2	814.3	0.025 SC/B
Finishing (F)		64.0	272.1	NS		143.8	754.7	NS