Anti-Inflammatory Effect of Curcumin on the Mouse Model of Myocardial Infarction through Regulating Macrophage Polarization

Figure 1

Curcumin attenuates adverse remodeling after MI: (a) 3-month overall survival analysis after MI; (b) quantitative analysis of infract size; (c) cardiomyocyte width; (d) myocardial fibrosis in border; (e) remote area; (f) qPCR analysis of ANP, BNP, and COL1A1 mRNA expression in the myocardium at 3 months post-MI. Data were shown as the . was vs. sham group, # was , and ns was vs. MI group. And value was calculated by the long-rank test in (a), Student’s -test in (b), and post hoc comparisons in (c–f).

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