Research Article
Extracellular HMGB1 Induced Glomerular Endothelial Cell Injury via TLR4/MyD88 Signaling Pathway in Lupus Nephritis
Figure 5
GLY treatment improved the injury of GECs in MRL/lpr mice. (a) Colocalization of CD31 (green) and SDC-1 (red) in mouse glomeruli cells was detected by IF staining. (b) The level of mouse plasma SDC-1 measured by ELISA (). (c) IHC showed the expression of VCAM-1 in mouse glomeruli. (d) The level of VCAM-1 in mouse plasma assessed by ELISA (). vs. LN group. (e) The level of NO in mice renal cortex ().
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