Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway

Figure 5

Effects of PQQ treatment on Th1, Th2, Th17, and Treg cells in peripheral blood and lung tissues of asthmatic model mice. (a and b) The gating strategy of flow cytometry for blood and tissue. (c and d) Representative scatter diagrams in flow cytometry and quantitative analysis of the percentages of CD4 + IFN-γ + T cells in blood and lung tissues. (e and f) Representative scatter diagrams in flow cytometry and quantitative analysis of the percentages of CD4 + IL-4+ T cells in blood and lung tissues. (g and h) Representative scatter diagrams in flow cytometry and quantitative analysis of the percentages of CD4 + RORγt+ T cells in blood and lung tissues. (i and j) Representative scatter diagrams in flow cytometry and quantitative analysis of the percentages of CD4 + CD25 + FoxP3+ T cells in blood and lung tissues. The columns and error bars represent the means and SEMs ( per group). , . Similar results were obtained in at least three independent experiments.

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