Research Article

Variation in Thyroid-Stimulating Hormone and Cognitive Disorders in Unmedicated Middle-Aged Patients with Major Depressive Disorder: A Proton Magnetic Resonance Spectroscopy Study

Table 3

Comparison of PFC and cerebellum biochemical metabolite ratios.

MDD groupHC group or value

NAA/Cr of right PFC-2.0600.044a0.117
Cho/Cr of right PFC-1.5570.125a0.203
NAA/Cr of left PFC-0.0810.936a0.936
Cho/Cr of left PFC-0.8330.409a0.545
Right cerebellum NAA/Cr-3.0150.004a0.032
Right cerebellum Cho/Cr-2.3860.017b0.068
Left cerebellum NAA/Cr-1.5260.127b0.203
Left cerebellum Cho/Cr-0.7080.479b0.547

PFC: prefrontal cortex; MDD: major depression disorder; HC: healthy control; NAA/Cr: N-acetylaspartate/creatine; Cho/Cr: choline/creatine. a-test, significant. bMann-Whitney test.