Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury

Figure 5

SGD induced a decline in M1-like markers and an elevation of M2-like markers. Luminex and qRT-PCR were performed to determine the expression of phenotypic markers in the sham, MCAO, and SGD groups at 24 h, 4 d, and 7 d after CI/RP. The corresponding statistical histograms of M1 markers, IL-1a (a, e), IL-1b (b, f), IL-6 (c, g), and the M2 marker IL-10 (d, h) are displayed. Results are presented as the , for Luminex, and for qRT-PCR in each group. ^#, ^## vs. sham; , vs. MCAO.

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